Ongoing Studies

Thermographic Imaging in Dogs with Intervertebral Disc Disease
Grossbard BP, Loughin CA, Marino DJ
Thermographic imaging is a non-invasive method used to screen animals for multiple medical problems. This study documents the use of thermal imaging to screen small breed dogs for possible herniated disc disease. Dogs with confirmed herniation based on MRI results are compared to dogs that have no evidence of a herniated disc. We also look at the usefulness of thermography to predict the site of herniation.

 

Treatment of Dogs with Primary Secretory Otitis Media
Grossbard BP, Loughin CA, Marino DJ
Primary secretory otitis media, also known as PSOM, is a disease of the inner ear. A mucous plug collects behind the ear drum, and can cause pain and scratching. Reported treatments have had variable success, and the mucous plug tends to recur. This study explores initial treatment with myringotomy followed by clavamox for 2 weeks.

 

Comparison between CT and MR for the Diagnosis of Primary Secretory Otitis Media in Dogs
Govier S, Loughin CA, Marino DJ
Primary secretory otitis media, also known as PSOM, is a disease of the inner ear. A mucous plug collects behind the ear drum, and can cause pain and scratching. Diagnosis has primarily depended on visualization of a pink swollen ear drum on examination of the ear canal. This type of examination can lead to missed diagnosis of PSOM since it is difficult to visualize this change. Recent studies have found that PSOM can easily be seen on a MRI, but MRIs are expensive and not widely available. This study looks at the accuracy of CT to diagnose PSOM.

 

The Prevalence of Primary Secretory Otitis Media in a Population of Cavalier King Charles Spaniels diagnosed with chiari-like malformation
Lugones M, Loughin CA, Marino DJ
Cavalier King Charles Spaniels constitute a breed that has a predisposition for PSOM and CLM, but “can these dogs have both diseases at the same time?” This study looks at a population of dogs being evaluated for CLM, and determines how prevalent PSOM is in this group of dogs.

 

Morphometric Features of the Craniocervical Junction Region in Dogs with Suspected Chiari-like Malformation Based on Combined MR and CT Imaging: 274 Cases (2007-2010)
Marino DJ, Loughin CA, Dewey CW, Marino LJ, Sackman J, Lesser M, Ackerman M
Evaluation of MRIs for CLM have mainly been based on the doctor’s opinion on how compressed and herniated the cerebellum may be. This kind of evaluation leads to considerable variability, resulting in disagreement among doctors. In order to make MRI evaluations more consistent, measurements made in the region of the skull and vertebrae of the neck have been developed. This paper reports  the consistency of these new measurements.

 

The Effect of Foramen Magnum Decompression and Cranioplasty on Syrinx Volume in Dogs with Chiari-like Malformation
Loughin CA, Marino DJ, Dewey CW
Syringomyelia, also called SM or syrinx, has been documented as a secondary occurrence to CLM. Based on multiple theories and the results of research in humans, we suspect that the syrinx will slowly regress after decompressive surgery. This paper looks at a group of dogs diagnosed with CLM and SM, and follows them for one year after surgery to see what happens to the length and volume of the syrinx over time.

 

Syrinx Location in Dogs with Chiari-like Malformation having Brain and Whole Spine MRI
Dewey CW, Loughin CA, Marino DJ
MRI studies of dogs thought to have CLM have included mainly the skull and neck, but does the syrinx exists further down the spinal cord? This study looks at a group of dogs with CLM and SM to see how far the syrinx can extend.


Histologic Findings on Dural Biopsies in Dogs with Foramen Magnum Decompression and Cranioplasty for Chiari-like Malformation
Loughin CA, Marino DJ, Peters R
Dural biopsies performed in humans with chiari-like malformation have shown thickening of the dura mater. Some of this thickening has even been described as “bone-like”. Do dogs with CLM exhibit the same changes of  the dura mater at the site of compression? This paper evaluates the biopsy reports of a group of dogs that have undergone surgery for CLM to determine if the dura develops “bone-like” qualities.
Last Updated ( Wednesday, 13 October 2010 12:41 )